Vuong C, et al. - A total of 521 patients treated at Loma Linda University Medical Center from April 2005 to July 2017 were analyzed to estimate the consequences of parathyroidectomy for primary hyperparathyroidism (PHPT) with nonlocalizing sestimibi and ultrasound scans. They noted similar complication rates among candidates with nonlocalized and localized disease, with a surgical cure for PHPT seen in 97.3% and 99.2% of them, respectively. They also found reduced preoperative parathyroid hormone and gland weight with nonlocalization. They recorded a higher incidence of multigland disease (MGD) in subjects with nonlocalization on sestamibi and ultrasound. They concluded that nonlocalization of parathyroid glands was not linked to a decline in cure rate or increased morbidity.