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Outcomes in children treated with pentobarbital infusion for refractory and super-refractory status epilepticus

Neurocritical Care Apr 04, 2018

Erklauer J, et al. - The impact of pentobarbital infusion for status epilepticus in children aged 0–17 years was retrospectively assessed between 2003 and 2016. In addition to mortality, the need for new medical technology assistance at hospital discharge and functional neurologic outcome were assessed using the pediatric cerebral performance category score (PCPC). High mortality was noted in this population. At discharge, some degree of disability was reported by most of the children. Survival was reported for some with good neurologic outcome despite the receipt of a prolonged pentobarbital infusion. At long-term follow-up, 36% of children demonstrated improvement in PCPC compared to discharge and 23% showed deterioration.

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