Winkler T, et al. - Researchers assessed the influence of a short (< 4 weeks) and long (≥ 4 weeks) interval on reinfection rate and functional outcome of hip and knee periprosthetic joint infection (PJI). Findings suggested similar outcome of two-stage exchange with short interval than with long interval when highly active antibiotic therapy is used. When strategies with a short interval were used patient inconvenience and care costs due to immobilization were found to be lower. Cumulatively additional 204 inpatient days for nursing care were required by the patients treated with long interval compared to patients with a short interval.