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Oropharyngeal cancer incidence and mortality trends in all 50 states in the US, 2001-2017

JAMA Otolaryngology—Head & Neck Surgery Dec 22, 2021

Damgacioglu H, Sonawane K, Zhu Y, et al. - Analyzing recent trends in oropharyngeal cancer (OPC) in all 50 US states and the District of Columbia, it was realized that there is a necessity for enhanced OPC prevention to combat increasing disease burden and mortality, and future research is also needed to understand geographic variations.

  • In this cross-sectional study, a total of 260 182 patients with OPC were analyzed.

  • A rise in OPC incidence, that is 2.7% per year during 2001 through 2017, has been noted among men, with the most pronounced increase (3.1% per year) witnessed for patients diagnosed with regional stage.

  • In males, rises of over 3.5% per year were noted to be largely clustered in the Southeastern and Midwestern states, and in females, an increment of over 2% per year was also mostly concentrated in the Southeast and Midwest.

  • In men, overall OPC incidence-based mortality rose 2.1% per year.

  • These observations indicate a continued national rise in OPC incidence in men in the US, with rapid increases among the elderly population.

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