Al Salman M, Ghiasi M, Taraz M, et al. - No additional therapeutic impacts were gained by adding oral simvastatin5 to narrowband UVB (NB-UVB) phototherapy in treating psoriasis, when compared with previous studies.

• A total of 48 psoriasis patients receiving NB-UVB phototherapy were randomized to oral simvastatin or placebo for 12 weeks.

• Relative to baseline, Psoriasis Area and Severity Index (PASI) score decreased significantly in both groups after 6 and 12 weeks.

• No significant differences in reducing PASI score and Dermatology Life and Quality Index were found between the two groups, neither at week sixth nor 12th.

• Comparison of both groups revealed an insignificant difference in the improvement of quality of life.