Kawasaki M, Ikeda Y, Ikeda E, et al. - As high levels of periodontopathic bacteria and Streptococcus anginosus have been found in cancer tissue in patients with esophageal cancer, the researchers in this study sought to clarify the features of the oral microbiota in patients with esophageal cancer. Participants in the study were 61 patients with esophageal cancer and 62 matched people without any cancers. In the cancer group, the prevalence of all bacteria, with the exception of F. nucleatum, in dental plaque; the prevalence of A. actinomycetemcomitans in saliva; the abundance of all bacteria, with the exception of F. nucleatum and P. intermedia, in dental plaque; and the abundance of A. actinomycetemcomitans and S. anginosus in saliva were significantly higher. The prevalence of T. forsythia and S. anginosus in dental plaque and of A. actinomycetemcomitans in saliva, as well as a drinking habit, were associated with a high risk of esophageal cancer, with a high odds ratio, as seen in logistic regression analysis.