Optimising the management of hypoglycaemia in people with type-2 diabetes. A randomised crossover comparison of a weight-based protocol compared with two fixed-dose glucose regimens
Diabetes, Obesity and Metabolism Feb 01, 2018
Krebs JD, et al. - Experts sought to determine whether an individualized body-weight based glucose treatment in adults with type-2 diabetes (T2DM) was more likely to resolve hypoglycaemia with a single treatment without excessive rebound hyperglycaemia compared to fixed doses of 12g or 30g glucose. Either a weight-based 0.3g/kg or a fixed 30g glucose treatment resulted in a higher blood glucose compared to a 12g treatment and increased the probability of resolution of hypoglycaemia after 10 minutes in T2DM. At 30 minutes, both treatments resulted in an excess of mild rebound hyperglycaemia (>8mmol/L).
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