Optimising prediction of early metastasis-free survival in uveal melanoma using a four-category model incorporating gene expression profile and tumour size
British Journal of Ophthalmology Feb 18, 2021
Roelofs KA, Grewal P, Lapere S, et al. - Since largest basal diameter (LBD) seems to have independent prognostic worth in uveal melanoma (UM), this topic is further studied herein among all patients undergoing plaque brachytherapy or enucleation for UM involving the choroid and/or ciliary body between 2012 and 2019. In total, 348 patients with a mean age of 60 ± 14 years were involved and followed for a mean of 40 ± 26 months (3.3 ± 2.2 years). The combination of the gene expression profile (GEP) and LBD allows patients to be separated into four easy-to-use prognostic groups and was similar to the model combining the American Joint Committee on Cancer stage with GEP.
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