Rimmer RA, Scott B, Pailet J, et al. - Because opioid abuse is a public health crisis, and the perioperative period can be a time of first opioid exposure, researchers wanted to learn more about postoperative pain management after endoscopic skull base surgery (ESBS). Between November 2019 and March 2020, adult patients undergoing ESBS were analyzed. Participants filled out preoperative questionnaires and were contacted every 48 hours after surgery to assess pain and opioid consumption. In total, 33 patients were selected and 28 of 33 patients (85%) underwent ESBS for sellar pathology. Greater total opioid use after ESBS was significantly associated with a history of headaches and prior opioid use within 60 days. Overall, opioid use decreased among all patients in the postoperative period, but a number of factors may have contributed to a longer duration of use.