Tenn MW, et al. - Researchers performed this post hoc analysis to determine the onset of action of loratadine tablets (ie unmodified) using data from a previously published Environmental Exposure Unit (EEU) study comparing azelastine nasal spray with loratadine tablets, cetirizine tablets, and placebo, by analyzing the total symptom score for the relief of nasal and ocular seasonal allergic rhinitis (SAR) symptoms. For the relief of nasal and ocular symptoms in adults with SAR, the onset of action of loratadine tablets was 75 min. Compared to previously reported studies which were conducted with modified (ie gelatin-encapsulated) loratadine tablets (180 min), results here indicated a faster onset of action for loratadine tablets (75 min).