Ore AS, Dombek GE, Cordova-Cassia CA, et al. - Researchers used data from the proctectomy-targeted National Surgical Quality Improvement Project file from 2016 to 2017, to determine if the lack of preoperative chemoradiotherapy or poor response to it was related to higher radial margin disease involvement among patients suffering from locally advanced rectal cancer, in this retrospective cohort study. This analysis involved 1,161 patients. Findings revealed elevated risk of radial margin positivity in relation to omission of indicated preoperative chemoradiotherapy or poor response to it. There is a requirement of more efforts for standardized rectal cancer care with the apt use of preoperative chemoradiotherapy.