Lago EG, Endres MM, Fiori HH, et al. - In view of the fact that retinochoroiditis is the most common manifestation of congenital toxoplasmosis, researchers sought to characterise the ocular outcome and factors that may affect these patients' visual prognosis. The sample consisted of patients with confirmed congenital toxoplasmosis seen between 1996 and 2017 in Porto Alegre, southern Brazil. Seventy-seven patients were involved, of which 65 (85.5%) were identified by regular screening. The value of long-term follow-up of patients with congenital toxoplasmosis is demonstrated by the high occurrence of new retinochoroidal lesions during the follow-up period. A protective factor against the later development of retinochoroiditis was the initiation of therapy within the first 4 months of life, particularly within the first 2 months. The high morbidity of congenital toxoplasmosis in Brazil was confirmed in spite of the usually favorable prognosis.