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Nutritional deficiencies and predictors of mortality in diabetic and nondiabetic gastroparesis

Annals of Gastroenterology Nov 25, 2021

Amjadi W, Qureshii W, Singhi RR, et al. - In gastroparesis, higher mortality was observed in relation to advanced age, coronary artery disease (CAD), chronic kidney disease (CKD), chronic obstructive pulmonary disease (COPD) and malnutrition. In this study population, the prevalence of nutritional deficiencies was high but consultation of a specialist nutritionist was uncommon.

  • This study involved 320 patients (mean age 47.5±5.3 years, 70% female, 71.3% Whites, 39.7% diabetic and 60.3% nondiabetic) with gastroparesis; of these, 46 (14.4%) died during the study span.

  • In patients with diabetes, higher mortality was observed in relation to advanced age (hazard ratio [HR] 1.06), CKD (HR 4.69), and malnutrition (HR 10.95).

  • In those without diabetes, an elevated mortality was noted in relation to factors such as older age (HR 1.05), CKD (HR 10.2), COPD (HR 7.5), CAD (HR 9.7), and malnutrition (HR 3.83).

  • Presence of vitamin D, vitamin B12, and iron deficiencies was found in 48.8%, 18.2% and in 50.8% of the participants, respectively.

  • A nutritionist evaluated only 19.4% of the whole cohort.

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