Lopez-Sublet M, et al. - Researchers investigated whether attenuation of physiological nocturnal decline of blood pressure (BP) - called nondipper pattern - is associated with subclinical cardiovascular and renal damage in an initially healthy population-based cohort study (the Stanislas Cohort Study). The STANISLAS Cohort is comprised of 1006 families (4295 subjects) recruited in 1993-1995 for a 5-year periodic health examination. Including a total of 1334 subjects from the 4th visit (2011-2016) of the STANISLAS cohort, they obtained data from 798 normotensive subjects (45±14 years, 395 (49%) nondippers, SBP/DBP mmHg 24h: 116/71±7/5) and 536 hypertensive patients (56±11 years, 257 (48%) nondippers, SBP/DBP mmHg 24h: 127/78±10/7). Analysis revealed no association of the nondipper pattern with increased cardiovascular or renal damage in this middle-aged population with an overall 24h-optimal BP control.