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Noncontrast computed tomography vs computed tomography perfusion or magnetic resonance imaging selection in late presentation of stroke with large-vessel occlusion

JAMA Nov 12, 2021

Nguyen TN, Abdalkader M, Nagel S, et al. - Among patients with proximal anterior circulation occlusion stroke presenting in the extended window, patients selected for thrombectomy with noncontrast computed tomography (CT) were compared with those selected with computed tomography perfusion (CTP) or magnetic resonance imaging (MRI), with respect to their outcomes at 90 days.

  • This is a multicenter cohort study of 1,604 patients in the extended window with large-vessel occlusion.

  • The clinical outcomes of patients selected with noncontrast CT did not differ significantly when compared with outcomes of those selected with CTP or MRI.

  • In view of these findings, researchers suggest a possible utility of noncontrast computed tomography alone as an alternative to advanced imaging in selecting patients with late-presenting large-vessel occlusion for mechanical thrombectomy.

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