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Non-adherence to antidepressants among older patients with depression: A longitudinal cohort study in primary care

Family Practice Nov 09, 2018

Holvast F, et al. - Researchers used the Netherlands Institute for Health Services Research (NIVEL) Primary Care Database to determine the rates of non-adherence to antidepressants among older adults in primary care, based on non-initiation, suboptimal implementation or non-persistence. The participants were all patients aged ≥60 years and diagnosed with depression in 2012. In primary care settings, older patients with depression had high non-adherence rates with regard to antidepressants. Better adherence was noted among those who were used to taking larger numbers of prescribed drugs, but this only explained part of the variance. GPs need to be mindful of the high rates of non-adherence. To improve adherence, it was suggested physicians emphasize the importance of adhering to the ideal length of antidepressant therapy.

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