Wing LMH, et al. - As pretreatment ambulatory blood pressure (ABP) vs office blood pressure (OBP) was found to be only a better predictor of outcome in placebo-treated participants in a previous clinical trial (Syst-Eur), researchers used Cox proportional hazards analysis to compare pretreatment ABP to OBP in terms of prediction of mortality over long-term (∼11 years) follow-up in treated elderly hypertensives from the Second Australian National Blood Pressure study (ANBP2), a comparative outcome trial in 6,083 off-treatment or previously untreated elderly hypertensives. At study entry in the ABP substudy, participants had ABP and nurse-performed OBP measurements. They observed a significant association of all-cause or cardiovascular deaths with pretreatment ABP, predominantly to night-time systolic ABP and pulse pressure, but not with OBP, in actively treated elderly hypertensives participating in ANBP2.