Mazeh H, et al. - In order to characterize the informative diversities in the miRNA expression profile of benign vs malignant thyroid nodules, researchers assessed the use of next-generation sequencing (NGS) technology. A panel of 19 miRNAs was identified with NGS technology. Findings suggested that these miRNAs can be used to distinguish benign from malignant thyroid nodules with indeterminate cytology, and that indeterminate thyroid nodules could be classified at higher accuracy than commercially available molecular tests. From 102 patients undergoing thyroidectomy, a total of 274 samples were obtained. Out of these samples, 71% were benign and 29% were malignant.