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Neutrophil-to-lymphocyte ratio and erythropoietin resistance among maintenance hemodialysis patients

Blood Purification Oct 20, 2021

Zhang J, Lu X, Wang S, et al. - In patients receiving hemodialysis (HD), a worse erythropoietin (EPO) responsiveness can be predicted by a higher neutrophil lymphocyte ratio (NLR) level (a cheaper method).

  • This analysis involved 299 HD patients to unveil the link between NLR and platelet lymphocyte ratio (PLR) and EPO responsiveness in this patient population.

  • EPO responsiveness was found to be positively associated with ferritin and negatively associated with serum albumin, lymphocytes, and hemoglobin.

  • On multivariate linear regression, a correlation with a higher erythropoiesis resistance index was shown by only NLR but not PLR.

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