Natural history of prediabetes in older adults from a population-based longitudinal study
Journal of Internal Medicine Jun 09, 2019
Shang Y, et al. - Researchers evaluated older adults for the rate at which prediabetes (defined as glycated hemoglobin [HbA1c] ≥5.7%) progresses to diabetes, leads to death, or returns to normoglycemia and (defined as HbA1c <5.7%) and prognostic factors linked to different prediabetes outcomes. For this population-based longitudinal study of Swedish older adults, 2,575 diabetes-free candidates (aged ≥60 years) were examined at baseline and followed for up to 12 years. According to findings, most older adults (42%) with prediabetes stayed stable or reverted to normoglycemia (22%) during a 12-year follow-up, while only one-third developed diabetes (13%) or died (23%). Reversal to normoglycemia may be aided by lower systolic blood pressure, lack of heart diseases, and weight management, indicating likely approaches for attaining normoglycemia in older adults with prediabetes.
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