Matsuhisa M, et al. - In Japanese patients with type 1 or type 2 diabetes mellitus (T1DM/T2DM), researchers contrasted nasal glucagon (NG) with intramuscular glucagon (IMG) for the treatment of insulin-induced hypoglycemia. Participants in the study were Japanese adults with T1DM/T2DM on insulin therapy, with hemoglobin A1c ≤ 10%. According to this phase 3, randomized, open-label, 2-treatment, 2-period crossover noninferiority study, in Japanese patients with T1DM/T2DM, NG was noninferior to IMG for successful treatment of insulin-induced hypoglycemia, promoting the use of NG as a rescue treatment for severe hypoglycemia.