O’Donnell C, Ashland MD, Vasti EC, et al. - In this prospective, observational cohort study of the American Heart Association’s COVID‐19 Cardiovascular Disease Registry, researchers examined if an elevated NT‐proBNP concentration at admission is linked with elevated in‐hospital mortality.

• Among 4,675 patients hospitalized with COVID‐19, normal and elevated NT‐proBNP cohorts were formed.

• Relative to patients with normal values, those with elevated NT‐proBNP (n = 1,344; 28.7%) were older, with more cardiovascular risk factors, and had a significantly higher rate of in‐hospital mortality (37% vs 16%) and shorter median time to death (7 vs 9 days).

• Risk of in‐hospital mortality and other complications appeared to be higher in correlation with elevated NT‐proBNP in patients with and without heart failure.