Wiese S, et al. - In this prospective study, the researchers examined the presence of diffuse myocardial fibrosis and determined the relation to disease severity, cardiac function and outcome. Fifty-two cirrhotic patients and 10 healthy controls were included in this investigation. For this analysis, all patients underwent cardiac MRI (CMR) with extracellular volume (ECV) quantification, tissue Doppler echocardiography, and biochemical assessments. Findings revealed that myocardial ECV was increased in patients with cirrhosis and seems related to disease severity and transplant-free survival. These changes most likely reflect subclinical diffuse myocardial fibrosis and could represent a structural element of cirrhotic cardiomyopathy.