Multiple linear regression analysis of the impact of corneal epithelial thickness on refractive error post corneal refractive surgery
American Journal of Ophthalmology Dec 06, 2019
Cho Y, Hieda O, Wakimasu K, et al. - By performing this retrospective, single-center, cross-sectional analysis, researchers assessed how the deviation from the targeted refraction (refractive error [RE]) post corneal refractive surgery is affected by the corneal epithelial thickness (CET). The participants included 211 eyes of 211 patients who were recruited from the Baptist Eye Institute, Kyoto, Japan, where they earlier had laser-assisted in situ keratomileusis (LASIK) or epipolis LASIK for the correction of myopia and myopic astigmatism from August 2000 to May 2014. These patients finally underwent CET evaluation via optical coherence tomography imaging of 17 zones (central: n = 1 zone, paracentral: n = 8 zones, and midperipheral: n = 8 zones) within a 6.0-mm-diameter area of the central cornea from April 2014 to February 2015. A significant effect of the difference of mean CET between the central and midperipheral zones on RE was revealed in multiple linear regression analysis. This implies a possible role of the difference between CET at the central and midperipheral zones in the final RE after corneal refractive surgery.
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