Weber JJ, et al. - In the setting where determining extent of residual disease is key for surgical planning after neoadjuvant chemotherapy (NAC), herein researchers assess the reliability of MRI in predicting pathologic complete response (pCR) of the breast primary and axillary nodes following NAC. Observations suggest radiologic complete response by MRI as not predictive of pCR with adequate accuracy to replace pathologic evaluation of the breast tumor and axillary nodes.