Katsanos AH, Malhotra K, Goyal N, et al. - Researchers analyzed aggregate data from all accessible randomized controlled clinical trials to assess the risk of 3-month mortality in correlation with mechanical thrombectomy (MT) + best medical therapy (BMT) vs BMT in patients with acute ischemic stroke with large vessel occlusion. They also investigated potential predictors on the mortality risk and carried out univariate meta-regression analyses. They found 11 eligible trials including 2,460 patients. The pooled rates of 3-month mortality were 15% (95% CI:12%–19%) in the MT + BMT group and 19% (95% CI:16%–23%) in the BMT group. A reduction in the risk of 3-month mortality was evident in relation to treatment with MT + BMT vs BMT alone, as revealed in the meta-analysis. This link seemed not to be moderated by individual patient or procedural features.