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Mortality in children with classic congenital adrenal hyperplasia and 21-hydroxylase deficiency (CAH) in Germany

BMC Endocrine Disorders Jun 14, 2018

Dörr HG, et al. - Researchers collected data from deceased congenital adrenal hyperplasia (CAH) children in Germany, as well as reviewed the cases in an attempt to determine the factors that may have contributed to their death. They performed a survey among Paediatric Endocrinologists in Germany to report on deceased children with CAH. Findings revealed that almost all deaths could be related to an inadequate administration of stress doses of hydrocortisone according to the assessments by the attending centres. Researchers assumed the effectiveness of educational programs over the past years since no deceased CAH children were reported in Germany from 2005 on.
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