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Monosodium urate burden assessed with dual-energy computed tomography predicts the risk of flares in gout: A 12-month observational study

Arthritis Research & Therapy Sep 21, 2018

Pascart T, et al. - Authors ascertained whether the extent of monosodium urate (MSU) burden measured with dual-energy computed tomography (DECT) and ultrasonography (US) is predictive of the risk of gout flares. They noted a 2.03-fold increase in the risk of flare during the first 6 months after initial assessment for each 1-cm3 increase in DECT MSU volume in foot deposits, and also found that the extent of MSU burden measured with DECT but not US was predictive of the risk of gout flares. Findings suggested that 0.81 cm3 to be the threshold volume best discriminating patients with and without flare.

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