Benfari G, et al. - Researchers carried out this study to examine whether the quantification of mitral regurgitation (MR) revealed an association with pulmonary hypertension (PH) in patients with aortic valve stenosis (AS). Effective regurgitant orifice area (ERO) was found to have an independent association with PH in patients with MR and a wide range of AS severity. The role of MR quantification also appeared stronger than other continuous variables commonly associated with left ventricular diastolic dysfunction, like E/e' ratio and left atrial volume.