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Mitosis count and number of cancer cells in cases of primary pulmonary adenocarcinoma: Correlations among phosphorylated histone 3, number of cancer cells, nuclear grade, pathologic features and prognosis

Pathology International Feb 12, 2018

Inoue T, et al. - The connection between the phosphorylated form of histone 3-stained mitotic figures [PHMFs] and clinical outcome of primary pulmonary adenocarcinoma was evaluated during this study. Researchers also undertook a comparative analysis of the results with findings for numbers of PHMFs and cancer cells. A strong link was brought to light between the number of cancer cells with the progression of Noguchi's classification and WHO pathologic type. The phosphorylated form of histone 3 (pHH3)/cancer-cell index exhibited an association with the prognosis, which was discovered to be beneficial for prognostic analysis of pulmonary adenocarcinoma patients.
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