Billmann F, Billeter A, Thomusch O, et al. - For localized primary hyperaldosteronism, a recognized risk factor for myocardial infarction, stroke, and atrial fibrillation, minimally invasive adrenalectomy is the first-line treatment. Researchers conducted a multicenter study investigating whether minimally invasive adrenalectomy should be performed using a cortex-sparing technique (partial minimally invasive adrenalectomy) or not (total minimally invasive adrenalectomy). Further, they investigated the morbidity linked with partial minimally invasive adrenalectomy vs total minimally invasive adrenalectomy. Among 234 matched patients with unilateral primary hyperaldosteronism, 78 (33.3%) were managed with partial minimally invasive adrenalectomy, and 156 (66.7%) with total minimally invasive adrenalectomy. Evidence gained suggests that for partial minimally invasive adrenalectomy, patients with unilateral primary hyperaldosteronism are good surgical candidates. Along with comparable surgical outcome to that of total minimally invasive adrenalectomy, there may be reduced postsurgical morbidity, particularly in terms of hypocortisolism and hypoglycemia.