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Minimally-invasive and targeted therapeutic cell delivery to the skin using microneedle devices

British Journal of Dermatology Sep 07, 2017

Gualeni B, et al. – This research aspired to examine the utility of hollow microneedle devices (to date only used for the delivery of drugs and vaccines into the skin and for the extraction of biological fluids) to deliver cells into the skin in a minimally–invasive, user–friendly and targeted fashion. This technique yielded an innovative and minimally–invasive method for delivering functional cells into the skin. Microneedle cell delivery served as a potential new therapeutic choice for cell therapy approaches including skin re–pigmentation, wound repair, scar and burn remodelling, immune therapies, and cancer vaccines.
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