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Mild cognitive impairment disrupts attention network connectivity in Parkinson's disease: A combined multimodal MRI and meta-analytical study

Neuropsychologia Evidence based | Mar 16, 2018

Bezdicek O, et al. - During this research, experts contemplated the neural correlates of mild cognitive impairment (MCI) in Parkinson's disease (PD) combining multimodal magnetic resonance imaging (MRI). Data did not display any differences in brain volume. The meta-analytic co-activation map (MACM) and overlap analyses demonstrated that the observed connectivity changes were localized in the hubs of the dorsal attention network, which aligned with the predominant attention deficit. Owing to PD, functional impairment in the dorsal attention network served as the hallmark of MCI, thereby adding to the previous findings of brain connectivity disruption in non-motor networks.
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