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Microperimetry in age-related macular degeneration: Association with macular morphology assessed by optical coherence tomography

British Journal of Ophthalmology Feb 06, 2019

Roh M, et al. - In this prospective, cross-sectional study, investigators estimated 102 eyes with AMD and 46 control eyes to assess the association between retinal sensitivity [estimated with macular integrity assessment (MAIA) microperimetry and optical coherence tomography (OCT)-based macular morphology] in age-related macular degeneration (AMD). They observed an association of older age, advanced AMD stage, and decreased retinal thickness with reduced mean retinal sensitivity. They found no relationship between choroidal thickness and retinal sensitivity within the macula. The appearance of ellipsoid disruption, subretinal fluid, atrophy and fibrosis, and outer retinal tubulation on OCT images was also correlated with a decline in retinal sensitivity when observed within the 10° diameter circle of the macula.
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