Pan SW, et al. - This work was performed with the aim to assess the predictors of persistent culture-positivity for Mycobacterium avium complex (MAC-PP) and its impact on radiographic deterioration in MAC lung disease (MAC-LD). Findings suggested the common occurrence of microbiological persistence in patients with MAC-LD. This persistence seemed to result in an increased risk of radiographic progression. Low BMI, NB pattern, and high acid-fast bacilli smear (AFS) grade were predictive of its persistence; in the presence of these risk factors, researchers suggested seriously considering anti-MAC treatment.