Amaro-Gahete FJ, et al. - Researchers conducted this 12 week-long, randomized controlled trial to contrasts the impact of different exercise training programs on basal metabolic rate and fat oxidation, in basal conditions (BFox) and during exercise (MFO), in sedentary, middle-aged adults (n = 71; aged 53.5 ± 4.9 years). Findings suggested that 12 weeks of high-intensity interval training plus whole-body electromyostimulation can increase the BFox and MFO of middle-aged sedentary adults. Such results have significant clinical implications; it may be possible to follow a well-designed high-intensity interval training regimen plus whole-body electromyostimulation to help combat the occurrence of chronic metabolic diseases marked by metabolic inflexibility in middle-aged sedentary adults, although it will be necessary to determine how long the effects last.