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Menopausal symptoms and surgical complications after opportunistic bilateral salpingectomy, a register-based cohort study

American Journal of Obstetrics and Gynecology Oct 18, 2018

Collins E, et al. - Researchers assessed the risk of surgical complications and menopausal symptoms performing bilateral salpingectomy in addition to benign hysterectomy. In addition, they compared hysterectomy+bilateral salpingectomy vs hysterectomy only in terms of time in surgery, perioperative blood loss/ blood transfusion, duration of hospital stay, and days to normal activities of daily living and days out of work. The uptake of opportunistic salpingectomy in Sweden was assessed secondarily. Findings revealed an increased risk of menopausal symptoms one year after bilateral salpingectomy at the time of hysterectomy.

Methods

  • Data from the National Quality Register of Gynecological Surgery in Sweden was used to perform this retrospective observational cohort study.
  • Researchers included women less than 55 years of age who had a hysterectomy for benign indications with or without bilateral salpingectomy in 1998-2016.
  • Multivariable regression models adjusting for possible confounding was used.

Results

  • During the study period, hysterectomy was performed on 23,369 women for benign indications.
  • An increased risk of menopausal symptoms (aRR 1.33, 95% CI 1.04, 1.69) was noted one year after hysterectomy with bilateral salpingectomy vs hysterectomy only.
  • Women having salpingectomy displayed longer hospital stay by 0.1 days (P=.01) and slightly reduced bleeding (-20 ml, P=.04).
  • Salpingectomy was not significantly correlated with other outcome measures, albeit there was a tendency towards higher risk of minor complications (aRR 1.30, 95% CI 0.93, 1.83).
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