Mefford MT, et al. - Researchers surveyed US adults with heart failure (HF) enrolled in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study, to assess behaviors and perceptions regarding taking medication with a specific focus on beta-blockers (BBs). Overall, 518 participants responded, and BB use was reported by 357 (69%). Taking ≥ 10 medications per day was reported by approximately half (42%) of the respondents. Although medication regimens were extensive, results revealed that responders were willing to take additional medications for their disease. A high recognition of BB use for treating HF and comorbidities was noted among the participants, but healthcare providers were not informed by many of the participants regarding the side effects. Overall, gaining a better understanding of patients’ medication-taking behaviors and perceptions could help optimize of HF treatments.