van Epps P, et al. - In routine clinical practice, researchers examined long-term adherence with tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) prescribed for pre-exposure prophylaxis (PrEP) to prevent HIV infection. They observed an overall high first-year adherence with TDF/FTC in a nationwide cohort of PrEP users. They identified differences in adherence by age, race, and sex which suggested potential for disparities in PrEP effectiveness in routine clinical practice.