• Profile
Close

Maternal obesity, pregnancy weight gain, and birth weight and risk of colorectal cancer

Gut Aug 29, 2021

Murphy CC, Cirillo PM, Krigbaum NY, et al. - In a population-based cohort of more than 18,000 mother-child dyads, in utero events are important risk factors for colorectal cancer (CRC) and may contribute to rising incidence rates in younger adults.

  • The Child Health and Development Studies are a prospective cohort of women who received prenatal care in Oakland, California between 1959 and 1966 (N =18,751 live births among 14,507 mothers).

  • Over the course of 738,048 person-years of follow-up, 68 offspring were diagnosed with CRC, with half (48.5%) being diagnosed before the age of 50.

  • Obesity in the mother (≥ 30 kg/m 2) increased the risk of CRC in the offspring.

  • Total weight gain altered the association of early weight gain rate, implying that discordant growth from early to late pregnancy increases risk.

  • Birth weight (≥ 4,000 g) was associated with a higher risk.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay