Joung KE, Rifas-Shiman SL, Oken E, et al. - Researchers conducted the study for analyzing the correlations of maternal 2 ^nd trimester and cord blood leptin and adiponectin levels with autism spectrum disorders (ASD) in offspring. Data were used from 1,164 mother-child pairs enrolled in Project Viva, a prospective pre-birth cohort. Data reported that the cumulative incidence of ASD was 3.4%. Maternal pre-pregnancy BMI (per 5 kg/m ²) was positively linked to ASD in a logistic regression model adjusted for maternal race/ethnicity, education, smoking status, and child sex. ASD was not associated with maternal leptin, cord blood leptin, or adiponectin levels. Pre-pregnancy BMI and adiponectin during pregnancy may be useful in monitoring the risk of autism. Prenatally increasing adiponectin levels may aid in the prevention of ASD.