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Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: National cohort study

American Journal of Obstetrics and Gynecology May 27, 2021

Gurol-Urganci I, Jardine JE, Carroll F, et al. - Researchers conducted a population-based cohort study in England with the aim to determine the correlation between SARS-CoV-2 infection at the time of birth and maternal and perinatal outcomes. From a national database of hospital admissions, they identified 342,080 women with a recorded singleton birth between May 29, 2020 and January 31, 2021. Of these women, 3,527 had a laboratory-confirmed SARS-CoV-2 infection. Outcomes revealed correlation of SARS-CoV-2 infection at the time of birth with higher rates of fetal death, preterm birth, preeclampsia and emergency Cesarean delivery. No additional adverse neonatal outcomes were observed, other than those related to preterm delivery. Based on these findings, they recommend counselling pregnant women regarding risks of SARS-COV-2 infection and considering them a priority for vaccination.

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