Villar J, Ariff S, Gunier RB, et al. - In this multinational cohort study involving 706 pregnant women with COVID-19 diagnosis and 1,424 pregnant women without COVID-19 diagnosis, researchers sought to assess the risks associated with COVID-19 in pregnancy on maternal and neonatal outcomes compared with not-infected, concomitant pregnant individuals. Women from 43 institutions in 18 countries were enrolled. Preeclampsia/eclampsia, severe infections, intensive care unit admission, maternal mortality, preterm birth, medically indicated preterm birth, severe neonatal morbidity index, and severe perinatal morbidity and mortality index were all higher risks for women with COVID-19. Fever and dyspnea of any duration were linked to an increased risk of severe maternal and neonatal complications. When pregnant women with and without COVID-19 diagnosis were compared in this multinational cohort study, COVID-19 in pregnancy was associated with consistent and significant increases in severe maternal morbidity and mortality, as well as neonatal complications. The findings should serve as a wake-up call to pregnant women and clinicians to strictly follow all COVID-19 prevention recommendations.