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Maternal and infant characteristics associated with maternal opioid overdose in the year following delivery

Addiction Feb 02, 2020

Nielsen T, Bernson D, Terplan M, et al. - Via performing a retrospective cohort study using a linked, population-level data set at Massachusetts, United States, researchers sought to determine the strength of the correlation between maternal and infant characteristics and postpartum opioid-related overdose. Among 174,517 women who delivered one or more live births from 2012 to 2014, 189 deliveries were reported among women experiencing ≥ 1 opioid overdose in the first year postpartum (11 of 10,000 deliveries). They observed postpartum opioid overdose in a positive correlation with the maternal diagnosis of opioid use disorder (OUD), prior non-fatal overdose, infant diagnosis of neonatal abstinence syndrome and high unscheduled health-care utilization. However, women without a diagnosis of OUD happened to receive more than half of postpartum overdoses in that period. Insufficient engagement in methadone or buprenorphine treatment in the month prior to delivery was observed hampering the reduction in the odds of postpartum overdose.
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