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Maternal and fetal outcomes associated with infective endocarditis in pregnancy

Clinical Infectious Diseases Jun 15, 2021

Dagher MM, Eichenberger EM, Addae-Konadu KL, et al. - This study was sought to evaluate whether maternal and fetal outcomes correlated with infective endocarditis in pregnancy. Researchers used the National Readmissions Database to obtain data between October 2015 and October 2018. In this study, billing codes distinguished admissions for infective endocarditis (IE) in female patients of reproductive age. They compared demographic characteristics, comorbidities, and outcomes were compared between patients with maternity-associated and non-maternity associated IE, and obstetric patients who delivered with and without IE. They used Weighted regressions to analyze outcomes in adjusted models. They distinguished 12,602 reproductive-aged female patients with a diagnosis of IE, of which 382 (weighted national estimate: 748) were maternity-associated. The findings revealed that maternity-associated IE does not seem to confer additional risk for adverse outcome over non-maternity-associated infection. The outcomes suggested that individuals delivering with IE have worse maternal and fetal outcomes than those whose deliveries are not complicated by IE.

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