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Masked hypertension and kidney function decline: The Jackson Heart Study

Journal of Hypertension Jun 05, 2018

Mwasongwe S, et al. - Since hypertension diagnosed by blood pressure (BP) measured in the clinic is associated with rapid kidney function decline (RKFD) and incident chronic kidney disease (CKD), researchers wanted to evaluate if the same associations existed with out-of-clinic measurements. The correlation of any masked hypertension (daytime SBP/DBP ≥ 135/85 mmHg, night-time SBP/DBP ≥ 120/70 mmHg, or 24-hour SBP/DBP ≥ 130/80 mmHg) with RKFD and incident CKD among African-Americans in the Jackson Heart Study was assessed. Participants had clinic-measured SBP/DBP less than 140/90 mmHg and completed ambulatory BP monitoring in 2000–2004. Findings demonstrated that an association may exist between masked hypertension and the development of CKD in African-Americans, while no association was found between masked hypertension and RKFD.

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