Nakatsuka Y, Murase K, Matsumoto T, et al. - Researchers intended to determine if there is an association between sleep-disordered breathing (SDB) severity and the surrogate markers of cardiovascular disease events varies in relation to the number of comorbidities. The sample consisted of 7,731 candidates. Candidates were stratified according to SDB severity and the number of comorbidities (hypertension, diabetes, dyslipidemia, and obesity), and the relationships between the maximum value of intima-media thickness of the common carotid artery (CCA-IMT-max), brachial-ankle pulse wave velocity, and cardio-ankle vascular index (CAVI) were assessed. According to this cross-sectional study, SDB severity is linked to the CCA-IMT-max level, but the independent connection becomes weaker for those with multiple comorbidities.