Ciocca L, et al. - Frameworks manufactured with a selective laser melting/milling hybrid technique (SLM/m) and conventional milling were examined for trueness and precision by comparing the implant-platform/framework interface with those of the original computer-aided design (CAD). Using a virtual 6-implant-supported full-arch framework CAD drawing, 3 independent manufacturing centers (n = 9/center) manufactured 27 titanium replicas using a hybrid SLM/m technology (labs 1 and 2) or the conventional milling technique (lab 3). Three-dimensional misfits were reported in all groups that were well within the error limits reported in the literature. New hybrid (SLM/milling) and conventional (milling) procedures differed significantly regarding the 3-dimensional misfits, with the milling technique the less accurate and precise. The most distant implants displayed the largest errors in all groups, resulting in a correlation between the framework span and the inaccuracies.