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Malignancy and mortality rates in patients with severe psoriatic arthritis requiring tumour-necrosis factor alpha inhibition: Results from the British Society for Rheumatology Biologics Register

Rheumatology Aug 29, 2018

Fagerli KM, et al. - Among a cohort of patients with severe psoriatic arthritis (PsA) receiving TNF inhibitor (TNFi), experts compared the incidence of cancer and all-cause and cause-specific mortality rates with those of the general UK population. Findings suggested similarity of the overall incidence of malignancy in this cohort of patients having severe PsA to that of the general population, nonetheless, the incidence of non-melanoma skin cancer was increased. In part, a significant increase in the all-cause mortality was seen due to excess of deaths attributed to coronary heart disease.
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