Wang J, Xinghua G., et al. - In patients with lower-grade gliomas (LGGs), researchers conducted this study for exploring the connections between magnetic resonance features and reverse-phase protein array (RPPA) subtypes (R1–R4). Using the Kaplan-Meier method and time-dependent receiver operating characteristic curves, survival estimates for the Cancer Genome Atlas cohort were generated. In total, 153 patients with LGG and a brain MRI from The Cancer Imaging Archive were retrospectively analyzed. The RPPA3 subtype is a poor prognostic biomarker for overall survival in LGG patients. Preoperative radiogenomics analysis of magnetic resonance features can predict the RPPA subtype and may be clinically useful in tailoring management strategies in patients with LGG.